Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer

NEJM has two interesting articles on EGFR recepter mutations and response to targeted treatments. The first of these demonstrates the incidence of EGRF mutations in the NSCLC population, and highlights the known associated demographic characteristics: non or light female smokers with adenocarcinoma. The study also demonstrates increased benefit to erolotinib, a TKI targeting the receptor.

Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer