Bevacizumab for NF2 associated AN

An interesting article yesterday at NEJM, in which investigators at MGH gave bevacizumab to 10 patients with NF2 associated acoustic neuromas (vestibular schwannomas). 9/10 had reduction in tumor size after administration and 4/7 evaluable for changes in hearing had an improvement. Very interesting data, and may be useful in large tumors that would be difficult to treat with either surgery or RT.