Tuesday, October 12, 2010


Lancet Oncology -

An interesting review article on angiosarcoma in the Lancet Oncology this week: these difficult tumors often involve the radiation oncologist, either as a long term complication of prior therapy (classically breast radiation), or as treatment.


[Review] Angiosarcoma: "Angiosarcomas are rare soft-tissue sarcomas of endothelial cell origin that have a poor prognosis. They can arise anywhere in the body, most commonly presenting as cutaneous disease in elderly white men, involving the head and neck and particularly the scalp. They can be caused by therapeutic radiation or chronic lymphoedema and hence secondary breast angiosarcomas are an important subgroup. Recent work has sought to establish the molecular biology of angiosarcomas and identify specific targets for treatment."

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